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Publication - Dr. Cenek Kolar
[1] Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugate.
Kolar, Cenek; Czech, Joerg; Bosslet, Klaus; Seemann, Gerhard; Sedlacek, Hans- Harald; Hoffmann, Dieter. (Aventis Pharma Deutschland GmbH, Germany). U.S. 45(2003), 33 pp.
[2] Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugate.
Kolar, Cenek; Czech, Jorg; Bosslet, Klaus; Seemann, Gerhard; Sedlacek, Hans- Harald; Hoffman, Dieter. (Aventis Pharma Deutschland GmbH, Germany). U.S. (2002), 32 pp.
[3] Preparation of substrate-spacer-active substance prodrugs.
Bosslet, Klaus; Czech, Joerg; Hoffmann, Dieter; Kolar, Cenek; Tillequin, Francois; Florent, Jean Claude; Azoulay, Michel; Monneret, Claude; Jacquesy, Jean Claude; et al. (Behringwerke AG, Germany). Ger. Offen. (1994), 17 pp.
[4] Semisynthetic rhodomycins and anthracycline prodrugs.
Kolar, Cenek; Bosslet, Klaus; Czech, Joerg; Gerken, Manfred; Hermentin, Peter; Hoffmann, Dieter. Res. Lab. Behringwerke AG, Marburg, Germany. ACS Symposium Series (1995), 574(Anthracycline Antibiotics), 59-77.
[5] Preparation of glycopeptides as antithrombotics.
Kolar, Cenek; Stueber, Werner. (Behringwerke Aktiengesellschaft, Germany). Eur. Pat. Appl. (1993), 19 pp.
[6] Fusion proteins of monoclonal antibodies and β-glucuronidase for site- specific prodrug activation.
Seemann, Gerhard; Bosslet, Klaus; Czech, Joerg; Kolar, Cenek; Hoffmann, Dieter; Sedlacek, Hans Harald. (Behringwerke A.-G., Germany). Eur. Pat. Appl. (1992), 34 pp.
[7] Preparation of nonapeptides as gonodoliberin antagonists.
Koenig, Wolfgang; Sandow, Juergen; Kolar, Cenek. (Hoechst A.-G., Germany). Eur. Pat. Appl. (1992), 16 pp.
[8] The change in research for the therapy of tumors.
Sedlacek, H. Harald; Hoffmann, Dieter; Czech, Joerg; Kolar, Cenek; Seemann, Gerhard; Gussow, Detlef; Bosslet, Klaus. Res. Lab., Behringwerke, Marburg, Germany. Chimia (1991), 45(10), 311-16.
[9] Preparation of glycosylanthracyclinones.
Kolar, Cenek. (Behringwerke A.-G., Germany). Ger. Offen. (1991), 9 pp.
[10] Preparation of glycosyletoposides as anticancer prodrugs.
Kolar, Cenek; Czech, Joerg; Bosslet, Klaus; Seemann, Gerhard; Sedlacek, Hans Harald. (Behringwerke A.-G., Germany). Eur. Pat. Appl. (1991), 18 pp.
[11] Preparation of N-(methoxybenzyloxycarbonyl)anthracyclines as neoplasm inhibitors.
Kolar, Cenek; Dehmel, Konrad; Hoffmann, Dieter; Kraemer, Hans Peter; Gronau, Thomas. (Behringwerke A.-G., Germany). Eur. Pat. Appl. (1991), 14 pp.
[12] Preparation of etoposides as cytostatic agents.
Kolar, Cenek. (Behringwerke A.-G., Germany). Eur. Pat. Appl. (1990), 11 pp.
[13] Preparation of glucosaminylepipodophyllotoxins as anticancer agents.
Kolar, Cenek; Dehmel, Konrad. (Behringwerke A.-G., Germany). Ger. Offen. (1990), 9 pp.
[14] Semisynthetic ε-(iso)rhodomycins: a new glycosylation variant and modification reactions.
Kolar, Cenek; Kneissl, Guenther; Knoedler, Ursula; Dehmel, Konrad. Res. Lab., Behringwerke A.-G., Marburg, Germany. Carbohydrate Research (1991), 209 89-100.
[15] Preparation of rhodomycin derivatives with a modified sugar moiety as antitumor agents.
Kolar, Cenek; Kraemer, Hans Peter; Dehmel, Konrad. (Behringwerke A.-G., Germany). Ger. Offen. (1990), 10 pp.
[16] Semisynthetic β-rhodomycins: a new approach to the synthesis of 4-O- methyl-β-rhodomycins.
Kolar, Cenek; Dehmel, Konrad; Moldenhauer, Hans; Gerken, Manfred. Res. Lab., Behringwerke A.-G., Marburg, Germany. Journal of Carbohydrate Chemistry (1990), 9(6), 873-90.
[17] Synthesis of 4-O-methyl-β-rhodomycins using derivatives of 4-amino-4- deoxy and 3,4-diamino-3,4-dideoxy sugars.
Kolar, Cenek; Dehmel, Konrad; Moldenhauer, Hans. Res. Lab., Behringwerke A.-G., Marburg, Germany. Carbohydrate Research (1990), 208 67-81.
[18] Anthracycline oligosaccharides: facile stereoselective synthesis of 2,6- dideoxy-α-L-lyxo-hexopyranosides.
Kolar, Cenek; Kneissl, Guenther; Wolf, Heinz; Kaempchen, Thomas. Res. Lab., Behringwerke A.-G., Marburg, Germany. Carbohydrate Research (1990), 208 111-16.
[19] Semisynthetic ε-isorhodomycins: their synthesis using glycals and their structure-activity relationship.
Kolar, Cenek; Dehmel, Konrad; Kraemer, Hans Peter. Res. Lab., Behringwerke A.-G., Marburg, Germany. Carbohydrate Research (1990), 201(2), 249-59.
[20] Etoposide: a new approach to the synthesis of 4-O-(2-amino-2-deoxy-4,6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl- 4-epipodophyllotoxin.
Kolar, Cenek; Dehmel, Konrad; Wolf, Heinz. Res. Lab., Behringwerke A.-G., Marburg, Germany. Carbohydrate Research (1990), 206(2), 219-31.
[21] A new approach to the synthesis of etoposide (VP 16). Kolar, Cenek; Moldenhauer, Hans; Kneissi, Guenther.
Res. Lab., Behringwerke A.-G., Marburg, Germany. Journal of Carbohydrate Chemistry (1990), 9(5), 571-83.
[22] Preparation of rhamnosylated peptide amides as gonadoliberin antagonists.
Koenig, Wolfgang; Sandow, Juergen; Kolar, Cenek. (Hoechst A.-G., Germany). Ger. Offen. (1990), 7 pp.
[23] Photolytic N-mono-demethylation of rhodosaminylanthracyclinone type anthracyclines.
Hermentin, P.; Raab, Ernst; Paal, Michael; Gerken, Manfred; Kolar, Cenek; Boettger, Dirk; Berscheid, Hans Gerd. Res. Lab., Behringwerke A.-G., Marburg,Germany. Journal of Carbohydrate Chemistry (1990), 9(2-3), 235-52.
[24] Semisynthetic 4-O-methyl-β-rhodomycins: synthesis and structure-activity relationships.
Kolar, Cenek; Gerken, Manfred; Kraemer, Hans Peter; Krohn, Karsten; Linoh, Haryanto. Res. Lab., Behringwerke A.-G., Marburg, Germany. Journal of Carbohydrate Chemistry (1990), 9(2-3), 223-34.
[25] Preparation of cytostatic cis-platinum complexes with 2-substituted-1,3- diaminopropane ligands.
Kolar, Cenek; Kraemer, Hans Peter; Dehmel, Konrad. (Behringwerke A.-G., Germany). Ger. Offen. (1990), 10 pp.
[26] Preparation of morpholine moiety-containing modomycin derivatives as antitumor agents.
Kolar, Cenek; Kraemer, Hans Peter; Gerken, Manfred; Knoedler, Ursula; Hermentin, Peter. (Behringwerke A.-G., Germany). Ger. Offen. (1990), 12 pp.
[27] Semisynthetic rhodomycins: new glycosiation methods for the synthesis of anthracycline oligosaccharides.
Kolar, Cenek; Kneiss, Guenther. Behringwerke A.-G., Marburg, Germany. Angewandte Chemie (1990), 102(7), 827-8.
[28] Process for preparing 4-O-alkyl-rhodomycines and their use for the preparation of 7-O-glycosylrhodomycinones.
Kolar, Cenek. (Behringwerke A.-G., Germany). Eur. Pat. Appl. (1990), 15 pp.
[29] Preparation of anthracycline derivatives as antitumor agents.
Kolar, Cenek; Gerken, Manfred; Kraemer, Hans Peter; Hermentin, Peter; Krohn, Karsten; Linoh, Haryanto. (Behringwerke A.-G., Germany). Ger. Offen. (1990), 10 pp.
[30] Preparation of anthracycline derivatives as cytotoxic agents.
Hermentin, Peter; Kraemer, Hans Peter; Hoffmann, Dieter; Kolar, Cenek; Raab, Ernst; Gerken, Manfred; Stache, Ulrich. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1989), 16 pp.
[31] Semisynthetic ε-isorhodomycins. Glycosylation and modification reactions.
Kolar, Cenek; Dehmel, Konrad; Knoedler, Ursula; Paal, Michael; Hermentin, Peter; Gerken, Manfred. Res. Lab., Behringwerke A.-G., Marburg, Fed. Rep. Ger. Journal of Carbohydrate Chemistry (1989), 8(2), 295-305.
[32] Synthesis and structure elucidation of p-methoxybenzoyl derivatives of rhodomycins.
Hermentin, Peter; Raab, Ernst; Paal, Michael; Boettger, Dirk; Berscheid, Hans Gerd; Gerken, Manfred; Kolar, Cenek. Res. Lab., Behringwerke A.-G., Marburg, Fed. Rep. Ger. Journal of Carbohydrate Chemistry (1989), 8(2), 255-63.
[33] Synthesis of 2'-iodo analogs of β-rhodomycins.
Gerken, Manfred; Blank, Sabine; Kolar, Cenek; Hermentin, Peter. Res. Lab., Behringwerke A.-G., Marburg, Fed. Rep. Ger. Journal of Carbohydrate Chemistry (1989), 8(2), 247-54.
[34] Preparation of semisynthetic rhodomycins as cytostatic agents.
Gerken, Manfred; Kolar, Cenek; Kraemer, Hans Peter; Hoffmann, Dieter; Hermentin, Peter. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1988), 29 pp.
[35] Alkyl alkanoates, a method for their preparation, and vaccine adjuvants containing them.
Bernhardt, Dieter; Kolar, Cenek. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1988), 5 pp.
[36] Preparation of glycosylamino acids and peptides as glycosidase inhibitors.
Kolar, Cenek; Kessler, Horst; Kottenhahn, Matthias; Kling, Andreas. (Hoechst A.-G., Fed. Rep. Ger.). Ger. Offen. (1988), 7 pp.
[37] Preparation of cytostatic anthracycline derivatives.
Hermentin, Peter; Paal, Michael; Kolar, Cenek; Kraemer, Hans Peter; Hoffmann, Dieter; Berscheid, Hans Gerd; Boettger, Dirk. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1989), 12 pp.
[38] Neoplasm inhibitors containing lipophilic anthracyclines.
Hoffmann, Dieter; Kraemer, Hans Peter; Hermentin, Peter; Gerken, Manfred; Kolar, Cenek. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1988), 5 pp.
[39] Glycosylated gonadoliberin analogs and their preparation as fertility agents.
Koenig, Wolfgang; Sandow, Juergen; Kolar, Cenek. (Hoechst A.-G., Fed. Rep. Ger.). Ger. Offen. (1988), 19 pp.
[40] Preparation and testing of N-desmethylglycosylanthracyclines as neoplasm inhibitors.
Hermentin, Peter; Paal, Michael; Kraemer, Hans Peter; Kolar, Cenek; Hoffmann, Dieter; Gerken, Manfred; Berscheid, Hans Gerd; Boettger, Dirk. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1988), 16 pp.
[41] Preparation of glycosylisorhodomycinone derivatives as neoplasm inhibitors.
Kolar, Cenek; Paal, Michael; Hermentin, Peter; Kraemer, Hans Peter. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1988), 9 pp.
[42] Hydrophilic gonadoliberin analogs.
Koenig, Wolfgang; Kolar, Cenek; Sandow, Juergen. Hoechst A.-G., Frankfurt/Main, Fed. Rep. Ger. Peptide Chemistry (1988), Volume Date 1987, 591-6.
[43] Cisplatin complexes, procedure for their preparation, and pharmaceuticals containing these compounds.
Kolar, Cenek; Dehmel, Konrad; Kraemer, Hans Peter. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1988), 12 pp.
[44] Unusual reaction to glycosyl urethanes during synthesis of glyco peptides.
Kolar, Cenek; Knoedler, Ursula; Seiler, Fritz R.; Fehlhaber, Hans Wolfram; Sinnwell, Volker; Schultz, Michael; Paulsen, Hans. Behringwerke A.-G., Marburg, Fed. Rep. Ger. Liebigs Annalen der Chemie (1987), (7), 577-81.
[45] Glycosyl urethanes.
Kolar, Cenek. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1986), 30 pp.
[46] Preparation and use of glycopeptides.
Kolar, Cenek; Seiler, Friedrich; Knoedler, Ursula. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1986), 34 pp.
[47] Platinum(II) complexes with diamino sugars and their pharmaceutical compositions.
Kolar, Cenek; Kraemer, Hans Peter; Dehmel, Konrad. (Behringwerke A.-G., Fed. Rep. Ger.). Eur. Pat. Appl. (1986), 26 pp.
[48] Cis-platinum complexes with a pentaerythrital derivative as ligand.
Kolar, Cenek; Kraemer, Hans Peter; Dehmel, Konrad. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1986), 29 pp.
[49] 1-Azidoaldoses.
Ihiem, Joachim; Deger, Hans Matthias; Kolar, Cenek; Kreuzer, Matthias. (Hoechst A.-G., Fed. Rep. Ger.). Eur. Pat. Appl. (1986), 8 pp.
[50] NMR spectroscopic structure elucidation of glycopeptides with the COLOC technique.
Kessler, Horst; Bermel, Wolfgang; Griesinger, Christian; Kolar, Cenek. Inst. Org. Chem., Univ. Niederurselerhang, Frankfurt, Fed. Rep. Ger. Angewandte Chemie (1986), 98(4), 352-3.
[51] Glycerol ethers and their use.
Kolar, Cenek. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1984), 14 pp.
[52] β-D-Galactose derivatives and their use.
Kolar, Cenek. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1983), 31 pp.
[53] Cyclophosphamide derivatives and their use.
Eibl, Hansjoerg; Kolar, Cenek; Seiler, Friedrich Robert; Sedlacek, Hans Harald. (Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V., Fed. Rep. Ger.; Behringwerke A.-G.). Eur. Pat. Appl. (1983), 32 pp.
[54] Chemical compounds and their use as antigens or immunoadsorbents.
Kolar, Cenek; Paulsen, Hans; Jacquinet, Jean Claude. (Behringwerke A.-G., Fed. Rep. Ger.). Ger. Offen. (1982), 28 pp.
[55] Building units for oligosaccharides. XX. Synthesis of the oligosaccharide determinants of blood group substances of type 2 of the ABH system. Discussion of α-glycoside synthesis.
Paulsen, Hans; Kolar, Cenek. Inst. Org. Chem. Biochem., Univ. Hamburg, Hamburg, Fed. Rep. Ger. Chemische Berichte (1981), 114(1), 306-21.
[56] Oligosaccharide building units. Part XIX. Synthesis of tetrasaccharide chains of type 2 determinants of blood-group substances A and B.
Paulsen, Hans; Kolar, Cenek. Inst. Org. Chem. Biochem., Univ. Hamburg, Hamburg, Fed. Rep. Ger. Tetrahedron Letters (1979), (31), 2881-4.
[57] Building units for oligosaccharides. XVI. Synthesis of the oligosaccharide determinants of the blood-group substances of type 1 of the ABH system.
Paulsen, Hans; Kolar, Cenek. Inst. Org. Chem. Biochem., Univ. Hamburg, Hamburg, Fed. Rep. Ger. Chemische Berichte (1979), 112(9), 3190-202.
[58] Building-units of oligosaccharides. 14. Syntheses of tetrasaccharide chains of blood group substances A and B determinants.
Paulsen, Hans; Kolar, Cenek. Inst. Org. Chem. Biochem., Univ. Hamburg, Hamburg, Fed. Rep. Ger. Angewandte Chemie (1978), 90(10), 823-4.
[59] Building units for oligosaccharides, XII. Synthesis of the trisaccharide chain of blood group substance A type 1 determinant.
Paulsen, Hans; Kolar, Cenek; Stenzel, Wolfgang. Inst. Org. Chem. Biochem., Univ. Hamburg, Hamburg, Fed. Rep. Ger. Chemische Berichte (1978), 111(6), 2370-5.
[60] Building units for oligosaccharides, XI. Synthesis of α-glycosidically linked di- and oligosaccharides of 2-amino-2-deoxy-D-galactopyranose.
Paulsen, Hans; Kolar, Cenek; Stenzel, Wolfgang. Inst. Org. Chem. Biochem., Univ. Hamburg, Hamburg, Fed. Rep. Ger. Chemische Berichte (1978), 111(6), 2358-69.
[61] Building blocks for oligosaccharides. Part VIII. Synthesis of oligosaccharide units of blood group substances with terminal α-linked D- galactosamine groups.
Paulsen, Hans; Stenzel, Wolfgang; Kolar, Cenek. Inst. Org. Chem. Biochem., Univ. Hamburg, Hamburg, Fed. Rep. Ger. Tetrahedron Letters (1977), (32), 2785-8.
[62] Building units for oligosaccharides. 3. Synthesis of α-glycosidically linked disaccharides of D-galactosamine.
Paulsen, Hans; Kolar, Cenek; Stenzel, Wolfgang. Inst. Org. Chem. Biochem., Univ. Hamburg, Hamburg, Fed. Rep. Ger. Angewandte Chemie (1976), 88(14), 478.

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